eSAS | EARLY-STAGE ANESTHESIOLOGY SCHOLARS

Research

Anesthesiologists’ Role in the NIH Precision Medicine Initiative

Deep genetic sequencing has become ever cheaper and more efficient. Coupled with continued improvements in electronic medical records, we are inching ever closer to predicting clinical outcomes at the level of single patients. In 2015, the NIH launched an ambitious initiative to realize this potential, All of Us, previously known as the Precision Medicine Initiative, which aims to gather genetic and biological data as well as health outcomes of 1 million American volunteers.. We are pleased to post a lecture presented at the 2017 IARS meeting by Dr. Sachin Kheterpal MD, MBA, from the University of Michigan Medical School. Dr. Kheterpal is a rising star in our field, well known for his work in large data set clinical outcomes research- he is a member of the advisory panel for the National I...

The Reproducibility Crisis in Anesthesiology (and elsewhere)

Have you ever tried to replicate a published finding and failed? If you’re just starting out as a researcher, you might be inclined to blame yourself. Just as likely, though, that result you’re aiming to replicate is not true to begin with. Reproducibility issues in science and medicine are nothing new. The most egregious  examples involve outright forgery and capture headlines – in his prime, Jan Hendrik Schön was publishing in Science or Nature about every six weeks, supporting the idea that only huge lies are worth telling. Then, there are those like Dr. Hwang Woo Suk, the eminent South Korean stem cell biologist who mixed in actual feats of stem cell biology with gross ethical and sientific misconduct. In anesthesia & critical care, fraudulent science can have rea...

Funding Opportunities for Early Career Investigators at the NIGMS

  The NIH will almost certainly be your #1 source of support when it comes time to launch your indenpedent research program. The first steps are often the hardest. In related news, the average age for a first R01 grant is at an all time high of 46. The NIH has sought to address this over the years, defining Early Stage Investigators as a privileged category of applicants in 2008. More recently, the NIH has rolled out the Next Generation Researchers Initiative to complement a growing number of mechanisms aimed at developing junior investigators (not without some minor controversy). So, how can you avail yourself of these NIH-funded opportunities? We present to you, with permission, “Funding Opportunities for Early Career Investigators at the NIGMS”, presented at the IARS 20...

All for One and One for All: The Concept of Team Science

by Julie K. Freed, MD PhD I attended a colleague’s wedding in 2013. Not surprisingly, I was assigned to sit at the far back table with the other coworkers and their spouses. I will never forget meeting the physical medicine and rehabilitation physician. After we introduced ourselves and our specialties, in a very polite way, he chuckled and responded with “well, I don’t think our paths will cross that much in the future.” At the time I agreed. After all, why would a PM&R physician ever need to work with an anesthesiologist? Ironically, four years later, I am collaborating with researchers in PM&R. The unfortunate reality facing our specialty is that despite developing safe anesthetics and superior monitoring devices, changing patient demographics are resulting in a very unhealthy p...

From AUA, eSAS, FAER, IARS and SOCCA: Collaborative Research Initiative for Anesthesiology Clinical and Translational Science

Collectively AUA, eSAS, FAER, IARS and SOCCA are coordinating to form a multi-center clinical trials network to tackle pressing problems in “preoperative care/optimization, operating room management, postoperative management, perioperative critical care, peri- and post-partum care, and pain management.” As part of the instigation of that initiative, a Call for Letters of Intent has been issued to seek projects with outcomes relevant to clinical practice and society. Three projects will be selected to receive $15,000 in seed funding to allow them to be “further refined, strengthened and streamlined prior to submission to an NIH institute or another appropriate funding agency (e.g., PCORI).” Initial letters of intent are due December 31st 2017. Please see this attache...

Funding Mechanisms Designed to Transition to Scientific Indepedence

Finding the right audience and funding mechanism for your grant is high on the list of challenges facing early career investigators in anesthesiology. We at eSAS are very fortunate to have the support Dr. Alison Cole, PhD, Chief of the Pharmacological and Physiological Sciences Branch at the National Institute for General Medical Sciences (NIGMS). As part of her role at NIGMS, she administers grants in anesthesiology and peri-operative pain and has been an outstanding resource to many anesthesiologist-scientists. With her permission, we are posting her presentation, “Funding Mechanisms Designed to Transition to Scientific Independence”, presented at the IARS 2017 Annual Meeting in Washington, DC. Transition to Independence

Eight tips for applying for your first grant

by Catherine Chen, MD While I don’t claim to be an expert in grantwriting, I have learned a thing or two over the past few years that may be helpful to those just starting out. I wrote my first successful grant application—a FAER Research Fellowship Grant—when I was a 2nd year anesthesia resident. More recently, I applied for and received a FAER Mentored Research Training Grant. Although both required a lot of blood, sweat, and tears (I’m exaggerating, but only a little), the second grant was definitely easier to write than the first. Why the difference between my two grantwriting experiences? With the second grant, I had a much better understanding of the writing process, timeline and what made up the different components of the grant. It also helped that some parts of the grant, such as ...

Picking A Research-Oriented Anesthesiology Residency

by Boris Heifets, MD PhD You’re finishing med school. You did a PhD, or spent serious time doing research. You are shocked how much you love anesthesiology (not quite what you expected a few years ago). Somewhat less shocking: you alone, among your peers, are going down this road instead of a research-track residency in medicine/peds/path. Can you really combine a career in science and anesthesiology? How do you even know which residencies to apply to? You need some help with this. Congratulations on navigating to the eSAS site! It’s true; you are looking for advice from a stranger on the Internet about one of the key decisions of your professional life. Well, I’m happy to help. Chances are we have something in common: I did an MD/PhD (neuroscience), was dead set on a career in neurology u...

NIDUS Seeking Proposals for $50,000 Pilot Grants!

The Network for Investigation of Delirium across the U.S. (NIDUS) is offering two $50,000 pilot grants for proposals related to delirium research. The purpose of these awards is to encourage innovative research that will advance investigation in delirium and lead to future grant funding. Applications are due on Tuesday, August 15, 2017, 5:00pm EST. Proposals must be related to delirium research in the following priority areas: Risk factors, prognosis, outcomes; Pathophysiology, mechanisms, biomarkers, genomics and other –‘omics’ approaches; Diagnostic tools and phenomenology; Clinical interventions for prevention and treatment. Two application tracks are available: junior investigator track and established investigator track. Open to U.S.-based and international researchers. Please visit o...

Eight tips for obtaining research funding

Tips for Obtaining NIH Grant Funding Courtesy of Laure Aurelian, PhD, Stanford University School of Medicine   Have a good idea; consider issues, questions and controversies. Identify appropriate institute; talk to PO. Establish your independence potential. Define your priorities and achievements; training to complement. Generate relevant preliminary data. Discuss potential problems and pitfalls. Describe alternate strategies. Use clear and concise writing style; proofread and critique your own proposal Seek mentoring, enlist collaboration and read successful proposals models.

Lost Password

Register

Skip to toolbar